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Arginine catabolic mobile element : ウィキペディア英語版 | Arginine catabolic mobile element The arginine catabolic mobile element (ACME) is a mobile genetic element of ''Staphylococcus'' bacterial species. This genetic element provides for several immune modulating functions, including resistance to polyamines which serve as a non-specific immune response both on intact skin and following the inflammatory response in wound healing. Diverse ACME are present in several species of ''Staphylococcus'', including ''Staphylococcus epidermidis''. ==Association with virulent MRSA== ACME are not common among antibiotic sensitive ''S. aureus'' (MSSA). The elements for the most prominent MRSA ACME appear to have assembled recently in ''S. epidermidis'' into the speG-positive ACME which was transferred to virulent ''S. aureus'' during the evolution of the epidemic USA300 MRSA strain. This broadened the ability of ''S. aureus'' to colonize sites other than a specific part of the nose. This strain is able to persist on intact skin and is spread rapidly person-to-person. As a result, the speG-positive ACME is a particularly important element of MRSA pathogenesis.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Arginine catabolic mobile element」の詳細全文を読む
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